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Apidra® insulin glulisine [rDNA origin] injection
For U.S. Residents Only
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Apidra® Pen and Pump FAQs

The Apidra® SoloSTAR® Pen: FAQs

Can I share my pen with another patient?

No. You cannot share your pen with other patients. Your pen is for single patient use only.

Is it OK to use the same needle more than once when injecting Apidra® mealtime insulin?

No. Always attach a new sterile needle before each use. Using the same needle may cause contamination, air bubbles, and other problems such as needle blocks.

Do I use a new insulin pen every time I inject?

No. Each Apidra® SoloSTAR® pen contains 300 units of insulin. The opened (in-use) Apidra® SoloSTAR® pen needs to be discarded after 28 days. You should never use your Apidra® SoloSTAR® pen past its expiration date.

How do I store Apidra®?

Unopened Apidra® vials, cartridge systems and Apidra® SoloSTAR® should be stored in a refrigerator, 36°F-46°F (2°C-8°C). Protect from light. Apidra® should not be stored in the freezer and it should not be allowed to freeze. Discard if it has been frozen.

Unopened vials/cartridge systems not stored in a refrigerator must be used within 28 days.

The opened (in-use) Apidra® SoloSTAR® pen should NOT be refrigerated, but should be kept below 77°F (25°C) away from direct heat and light. The opened (in-use) Apidra® SoloSTAR® kept at room temperature must be discarded after 28 days.

What do I do if there is not enough insulin left in the pen for my injection?

If there isn't enough insulin for your full dose, you can complete your dose by calculating how much more you will need from a new pen. For example: If you normally use 41 units and there are only 12 units left in your pen, you will need 29 units from the new pen. Inject the remaining insulin from the first pen, and then inject the appropriate amount with the new pen to complete your dose. Or, you can just use a new pen for your full dose.

How do I take care of the Apidra® SoloSTAR® pen?

It's important to protect your pen from dust and dirt, so you can clean the outside of your Apidra® SoloSTAR® pen by wiping it with a damp cloth. Do not run it under water or use any soap or solvents.

How do I get the Apidra® SoloSTAR® pen?

The Apidra® SoloSTAR® pen is available by prescription only. Ask your healthcare professional if the Apidra® SoloSTAR® pen is right for you.


Apidra® in a Pump: FAQs

What is an insulin pump?

An insulin pump is a device about the size of a small cell phone. It continuously delivers small amounts of insulin through an infusion line placed under the skin. If using Apidra, the infusion set must be changed every 48 hours.

How do insulin pumps work?

An insulin pump has a reservoir that is filled with insulin and a microcomputer that allows you to adjust how much insulin is to be delivered. Pumps only use buffered short-acting or rapid-acting insulin (not long- or intermediate-acting insulin). Insulin is delivered continuously over 24 hours at a basal rate to keep your blood sugar levels in a normal range. You can program different amounts of insulin for different times of the day and night. When you eat, you use buttons on the pump to give you additional or "bolus" insulin to cover the carbohydrates in the meal.

Where do I put the insulin pump when I sleep?

When you sleep, you can try laying the pump next to you on the bed or even on a bedside table. Some pump wearers put it in a pocket in their pajamas or wear it on a waistband, armband, legband, or clip it to the blanket or pillow with a belt clip. Do what works best for you!

Can I take a bath or shower with an insulin pump?

Yes. Although insulin pumps are water resistant, you should not set them directly in water. Insulin pumps come with disconnect ports so they can easily be disconnected for showering, bathing, or swimming. Some pumps have special cases you can buy to place them in, which can be hung around your neck or on a shower faucet.

Is using Apidra® mealtime insulin in a pump right for me?

Talk with your healthcare professional to learn if Apidra® can help you better manage your mealtime blood sugar as part of your overall diabetes treatment plan, which includes diet, exercise, and other diabetes medications.

Where do I go to find my Direct Member Reimbursement form?

Just visit www.patientrebateonline.com to download the DMR form and start using your co-pay card to easily get reimbursed.

Prescription Apidra® is for adults with type 2 diabetes or adults and children (4 years and older) with type 1 diabetes to improve blood sugar control. Apidra® given by subcutaneous injection is usually used with a longer-acting insulin. When used as a mealtime insulin, Apidra® should be given within 15 minutes before or within 20 minutes after starting a meal.

Apidra® may be infused subcutaneously by external insulin infusion pumps.

Important Safety Information for Apidra® (insulin glulisine [rDNA origin] injection)

Do not use Apidra® during a low blood sugar reaction (hypoglycemia) or if you are allergic to any of the ingredients in Apidra®.

Do not share needles, insulin pens or syringes with others. Do NOT reuse needles.

You must test your blood sugar levels while using insulin, such as Apidra®. Do not make any changes to your dose or type of insulin without talking to your healthcare provider. Any change of insulin should be made cautiously and only under medical supervision. Apidra® must only be used if the solution is clear and colorless with no particles visible.

Please click here for additional Important Safety Information for Apidra®.

Please click here for Full Prescribing Information for Apidra®.

Important Safety Information for Apidra® (insulin glulisine [rDNA origin] injection)

Do not use Apidra® during a low blood sugar reaction (hypoglycemia) or if you are allergic to any of the ingredients in Apidra®.

Do not share needles, insulin pens or syringes with others. Do NOT reuse needles.

You must test your blood sugar levels while using insulin, such as Apidra®. Do not make any changes to your dose or type of insulin without talking to your healthcare provider. Any change of insulin should be made cautiously and only under medical supervision. Apidra® must only be used if the solution is clear and colorless with no particles visible.

Apidra®, when given by injection under the skin, should not be mixed with insulins other than NPH. Do not mix Apidra® with any insulin when used in the pump or for intravenous administration.

The most common side effect of insulin, including Apidra®, is low blood sugar (hypoglycemia), which may be serious. Some people may experience symptoms such as shaking, sweating, fast heartbeat, and blurred vision. Severe hypoglycemia may be serious and life threatening. It may cause harm to your heart or brain. Other possible side effects may include low blood potassium, injection site reactions, such as changes in fat tissue at the injection site, and allergic reactions, such as itching and rash. Less common, but potentially more serious or life-threatening, is generalized allergy to insulin, including anaphylactic reactions.

Tell your doctor about other medicines, especially ones commonly called TZDs (thiazolidinediones), and supplements you are taking because they can change the way insulin works. Before starting Apidra®, tell your doctor about all your medical conditions including if you have liver or kidney problems, are pregnant or planning to become pregnant, or are breast-feeding or planning to breast-feed. If you have heart failure or other heart problems, it may get worse while you take TZDs with Apidra®.

It is important to always follow the instructions provided with your Apidra® prescription for use with an external insulin infusion pump. These instructions may differ from the instructions that accompany your insulin infusion pump. Failure to follow the Apidra® specific instructions may lead to serious side effects.

You must change the infusion set (reservoir, tubing, and catheter), and the Apidra® in the pump reservoir at least every 48 hours. Do not mix Apidra® with any insulin when used in the pump and do not dilute Apidra®.

If the pump or infusion set does not work right or in case of handling errors, you may not get the right amount of insulin. This can cause low blood sugar (hypoglycemia), high blood sugar (hyperglycemia), high amounts of sugar and ketones in your blood (ketosis) or a build-up of acid in your blood because your body is breaking down fat instead of sugar (diabetic ketoacidosis). It is important to have another way to inject Apidra® in case the pump does not work.

Apidra® has not been studied in children with type 2 diabetes or in children younger than 4 years of age with type 1 diabetes. In a clinical study of children with type 1 diabetes, there was a higher rate of severe symptomatic hypoglycemia in the two treatment groups (Apidra® or insulin lispro) compared to adult trials with type 1 diabetes.

Apidra® SoloSTAR® is a disposable prefilled insulin pen. Please talk to your healthcare provider about proper injection technique and follow instructions in the Instruction Leaflet that accompanies the pen.

Indications and Usage for Apidra® (insulin glulisine [rDNA origin] injection)


Prescription Apidra® is for adults with type 2 diabetes or adults and children (4 years and older) with type 1 diabetes to improve blood sugar control. Apidra® given by subcutaneous injection is usually used with a longer-acting insulin. When used as a mealtime insulin, Apidra® should be given within 15 minutes before or within 20 minutes after starting a meal.

Apidra® may be infused subcutaneously by external insulin infusion pumps.

Click here for Full Prescribing Information for Apidra®.

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The health information contained herein is provided for general educational purposes only. Your healthcare professional is the single best source of information regarding your health. Please consult your healthcare professional if you have any questions about your health or treatment.

*Offer is not valid for patients if their prescriptions are paid in part or full by any state or federally funded programs, including, but not limited to, Medicare or Medicaid, Medigap, VA, DOD, or TriCare. Offer is not valid where prohibited by law. Sanofi US reserves the right to rescind, revoke, or amend this offer without notice. Maximum benefit is $100 off per prescription depending on your out of pocket costs for the duration of the program.

**"Certified Diabetes Educator" and "CDE" are certification marks owned and registered by the National Certification Board for Diabetes Educators (NCBDE). NCBDE is not affiliated in any way with Sanofi US (or your official designation). NCBDE does not sponsor or endorse any diabetes-related products or services.