FOR U.S. RESIDENTS ONLY

About Apidra®

What is Apidra?

Apidra is a fast-acting insulin that lowers blood sugar after meals.

Apidra should be taken within 15 minutes before or within 20 minutes after starting a meal.

Apidra is used to control high blood sugar in adults and children with diabetes.

Still getting used to your Apidra routine? Here are some tips for staying on track.

Remember your dose may change from meal to meal based on what and how much you eat. Talk with your healthcare professional about the Apidra dose that's right for you. Your dose will be based on what your body needs, your lifestyle, how much you exercise, your diet, and the other medications you take.

Ask your healthcare professional when you should check your blood sugar and keep a daily log of your levels. This will help you and your healthcare professional see what works and what doesn't.

If you have any questions about your insulin dose, talk to your healthcare professional right away. If mealtime insulin is new to you, it may take some time to get used to it, and that's okay.

We’re here to help

At TeamingUp for Diabetes, we believe that you can successfully manage your diabetes—partnering with your healthcare provider and with the right team behind you. As part of your team, we offer information, recipes, tools, and tips that are helpful and motivating.

See How It Works

There are 3 ways to administer Apidra. See what method works best for you.

Dosing and Support

Find out how Apidra provides dosing flexibility around mealtime to work for you.

Savings Offers

Learn how eligible patients with and without insurance can save on Apidra.

Indications and Usage for Apidra® (insulin glulisine injection)

Prescription Apidra is a fast (rapid) acting insulin used for adults and children with diabetes mellitus to control high blood sugar. It is not known if APIDRA is safe or effective in children less than 4 years of age with type 1 diabetes or in children with type 2 diabetes.

When used as a mealtime insulin, Apidra should be given within 15 minutes before or within 20 minutes after starting a meal.

Apidra may be infused subcutaneously by external insulin infusion pumps.

Important Safety Information for Apidra® (insulin glulisine injection)

Do not use Apidra if you have low blood sugar reaction or if you are allergic to insulin glulisine or any of the ingredients in Apidra.

Do not share needles, insulin pens or syringes with others even if the needle is changed. Do NOT reuse needles. You may give other people a serious infection, or get a serious infection from them.

Before starting Apidra, tell your doctor about all your medical conditions, including if you have liver or kidney problems, if you are pregnant or planning to become pregnant or if you are breastfeeding or planning to breastfeed.

Heart failure can occur if you are taking insulin together with pills called TZDs (thiazolidinediones), even if you never had heart failure or other heart problems. If you have heart failure, it may get worse while you take TZDs with Apidra. Your treatment with TZDs and Apidra may need to be changed or stopped by your doctor if you have new or worsening heart failure. Tell your doctor if you have new or worsening symptoms, including:

  • Shortness of breath
  • Sudden weight gain
  • Swelling of your ankles or feet

Tell your doctor about all medications you take, including OTC medicines, vitamins, supplements, and herbal supplements.

When used a mealtime insulin, Apidra should be taken within 15 minutes before a meal or within 20 minutes after starting a meal. Test your blood sugar levels as directed by your doctor when using Apidra. Do not change your dose or type of insulin without talking to your doctor. Any change of insulin should be made cautiously and only under medical supervision.

Check your insulin label to verify that you have the correct insulin before each injection. Use Apidra only if the solution is clear and colorless with no particles visible.

While using Apidra, do not drive or operate heavy machinery until you know how Apidra affects you. Do not drink alcohol or use medicines that contain alcohol.

Apidra may cause serious side effects that can lead to death, including:

  • Low blood sugar (hypoglycemia). Signs and symptoms of low blood sugar may include dizziness or light-headedness, sweating, confusion, headache, blurred vision, slurred speech, shakiness, fast heartbeat, anxiety, irritability or mood changes, hunger.
  • Serious allergic reactions. Get medical help right away if you have: a rash over your whole body, shortness of breath, trouble breathing, fast pulse, sweating or feeling faint
  • Low potassium in your blood (hypokalemia). Your doctor should monitor you for low blood potassium levels.
  • Heart failure. Your doctor should monitor you closely while you are taking TZDs with Apidra.

Get emergency medical help if you have:

  • Trouble breathing, shortness of breath, fast heartbeat, swelling of your face, tongue, or throat, sweating, extreme drowsiness, dizziness, confusion.

The most common side effects of APIDRA include: low blood sugar (hypoglycemia), weight gain, itching, rash, swelling, allergic reactions including injection site reactions, skin thickening or pits at the injection site (lipodystrophy)

Important Safety Information for Apidra® (insulin glulisine injection) SoloStar

Apidra SoloSTAR is a disposable prefilled insulin pen. Please talk to your healthcare provider about proper injection techniques and follow instructions in the Instruction Leaflet that accompanies the pen.

Important Safety Information for Apidra® (insulin glulisine injection) when used in a pump

Replace the infusion sets (reservoir, tubing, and catheter), and the Apidra in the reservoir at least every 48 hours and select a new infusion site. Do not mix or dilute Apidra when used in the pump. Failure of your insulin pump or infusion set or degradation of the insulin in the pump can cause hyperglycemia and ketoacidosis. Always carry an alternate form of insulin administration in the case of pump failure.

Click here for Full Prescribing Information for Apidra®.
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If you are a patient experiencing problems with a Sanofi US product, please contact Sanofi US at 1-800-633-1610.

The health information contained herein is provided for general education purposes only. Your healthcare professional is the single best source of information regarding your health. Please consult your healthcare professional if you have any questions about your health or treatment.

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*Eligibility Restrictions
This offer is not valid for prescriptions covered by or submitted for reimbursement under Medicare, Medicaid, VA, DOD, TRICARE, or similar federal or state programs including any state pharmaceutical assistance program. Important to note that if you have an Affordable Care (Health Care Exchange) plan, you may still be qualified to receive and use this savings card. Please note: the Federal Employees Health Benefits (FEHB) Program is not a federal or state government health care program for purposes of the savings program. This program is not valid where prohibited by law.

Offer Terms for Apidra $0 Co-pay Savings Card
For the duration of the program, the Savings Card offers a $0 copay with a maximum savings up to $600 per box for prescriptions covered by private or commercial insurance. This offer is valid for up to 3 boxes per prescription.

Offer Terms for Insulins Valyou Savings Program ($149/$99)
For the duration of the program, eligible patients will pay $149 for each pack of pens or $99 for each vial. Maximum quantity of ten packs of pens or ten vials per fill. Offer is valid for one fill per month. When using the Insulins Valyou Savings Card, prices are guaranteed for 12 consecutive monthly fills. This offer is not valid for the Max SoloStar pen. The Insulins Valyou Savings Program applies to the cost of medication. There are other relevant costs associated with overall treatment.

Savings may vary depending on patients’ out-of-pocket costs. Upon registration, patients receive all program details. Sanofi US reserves the right to change the maximum cap amount, rescind, revoke, or amend the program without notice.

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This site is intended for use by U.S. residents only.

SAUS.GLU.18.12.7369b Last Update: February 2019

Important Safety Information for Apidra® (insulin glulisine injection)

Do not use Apidra if you have low blood sugar reaction or if you are allergic to insulin glulisine or any of the ingredients in Apidra.

Do not share needles, insulin pens or syringes with others even if the needle is not changed.
Do NOT reuse needles. You may give other people a serious infection, or get a serious infection from them.