FOR U.S. RESIDENTS ONLY

How to Use

How do you take Apidra®?

There are 3 ways to administer Apidra

The Apidra SoloSTAR® Pen

Learn how to use the Apidra SoloSTAR Pen. Check out this step-by-step guide to become a Pen pro.

Expand All | Collapse All

PLEASE REVIEW THE FULL INSTRUCTIONS FOR USE OF THE APIDRA (INSULIN GLULISINE INJECTION 100 UNITS/ML) SOLOSTAR PEN THAT COME WITH YOUR PRESCRIPTION.

PREPARE FOR AN INJECTION

Before beginning, check the label on the insulin pen to ensure you are using the correct insulin.

ATTACH A NEW NEEDLE

Keep the needle straight as you attach it. Apidra SoloSTAR uses push-on or screw-on needles.

PERFORM A SAFETY TEST

This removes air bubbles and ensures that the pen and needle are working properly. Select a dose of 2 units. Always perform the safety test before each injection.

Take off the outer needle cap and keep it to remove the used needle after your injection. Then take off the inner needle cap and discard it.

Hold the pen with the needle pointing upward. Tap the reservoir gently so any air bubble rise up to the needle.

Press the injection button all the way in. Check if insulin comes out of the needle. If insulin does not come out, check for air bubbles and repeat the test 2 more times to remove them. If no insulin comes out after the third time, try again with a new needle.

SELECT YOUR DOSE

Be sure the dose window shows “0” following the safety test. Select your required dose in 1-unit steps. If you need a dose larger than 80 units, use 2 or more injections.

INJECT YOUR DOSE

Using the method your healthcare professional showed you, insert the needle into the skin in either your upper arm, abdomen (stomach area), or thigh (upper leg).

Press the injection button in all the way. Hold the button in that position, slowly count to 10, then withdraw the needle.

REMOVE THE NEEDLE

Always remove the needle after each injection. Put the outer needle cap back on the needle and use it to unscrew the needle from the pen. Dispose of the needle safely, as instructed by your healthcare provider (e.g. in a sharps container). Put the cap on the pen.

If you can’t dial the dose you want, check to see if you have enough insulin in the reservoir.

If you have any other problems with the pen, first try changing the needle and repeating the safety test.

Each Apidra SoloSTAR is for use by one person only.

You should carefully read the instruction leaflet that comes with your pen for additional important information.

Apidra vial and syringe

Learn how to take Apidra with a syringe and vial by reading the instructional step-by-step injection guide.

Expand All | Collapse All

PLEASE REVIEW THE FULL INSTRUCTIONS FOR USE OF THE APIDRA (INSULIN GLULISINE INJECTION 100 UNITS/ML) VIAL THAT COME WITH YOUR PRESCRIPTION

REMOVE THE CAP

If you are using a new vial of Apidra (insulin glulisine injection 100 Units/mL), remove the protective cap. Leave the stopper in place.

STERILIZE THE TOP

Wipe off the top of the vial with a clean alcohol swab.

DRAW AIR INTO THE SYRINGE

Take the syringe and pull the plunger to draw in an amount of air equal to your Apidra dose.

INJECT AIR INTO THE VIAL

Push the needle through the stopper in the vial’s top and push the plunger to inject the air into the vial.

DRAW UP THE DOSE

Leave the syringe in the vial and turn both upside down. Hold the syringe and vial firmly in one hand. Make sure the tip of the needle is in the insulin. With your free hand, pull the plunger to withdraw the correct dose into the syringe.

CHECK FOR BUBBLES

Before you withdraw the needle out of the vial, check the syringe for air bubbles.

TAP TO RELEASE

If you see any air bubbles in the Apidra solution, hold the syringe straight up and tap the side of the syringe until the air bubbles rise to the top.

EJECT THE AIR

Gently push the air bubbles and insulin all the way out with the plunger. Then draw the correct dose back into the syringe.

REMOVE THE NEEDLE

Pull the needle out of the vial. Do not let the needle touch anything. You’re now ready to inject.

PICK YOUR SPOT

Choose an area of your skin to be injected: either your upper arm, thigh or stomach area. Be sure to rotate sites within the area from one injection area to the next.

CLEAN YOUR SKIN

Use rubbing alcohol or an alcohol pad to clean the skin where you are going to inject. Alcohol can sometimes sting if it’s not completely dry when you inject, so wait a few seconds for it to evaporate or pat the area dry with a sterile cotton ball.

PINCH A FOLD OF SKIN

Pinch the skin and hold it. Insert the needle straight into the pinched skin the way your healthcare professional showed you.

PLEASE REVIEW THE FULL INSTRUCTIONS FOR USE OF THE APIDRA (INSULIN GLULISINE INJECTION 100 UNITS/ML) VIAL THAT COME WITH YOUR PRESCRIPTION

ADMINSTER INJECTION

Push the plunger slowly to inject the full dose of Apidra. Leave the needle in the skin for 10 seconds.

WITHDRAW THE NEEDLE

Pull the needle straight out and apply gentle pressure to the spot where you injected for several seconds. Don’t rub the area.

DISCARD MATERIALS SAFELY

Follow your healthcare professional’s instructions for throwing away the needle and syringe.

Apidra in a pump

It is important to change the Apidra reservoir at least every 48 hours to reduce the risk of pump clogs.

Need more information about using Apidra in a pump? Go to the FAQS

Dosing and Support

Find out how Apidra provides dosing flexibility around mealtime to work for you.

Savings Offers

Learn how eligible patients with and without insurance can save on Apidra.

About Apidra

Learn how Apidra can help control blood sugar at mealtime and gives you dosing flexibility around mealtime.

Indications and Usage for Apidra® (insulin glulisine injection)

Prescription Apidra is a fast (rapid) acting insulin used for adults and children with diabetes mellitus to control high blood sugar. It is not known if APIDRA is safe or effective in children less than 4 years of age with type 1 diabetes or in children with type 2 diabetes.

When used as a mealtime insulin, Apidra should be given within 15 minutes before or within 20 minutes after starting a meal.

Apidra may be infused subcutaneously by external insulin infusion pumps.

Important Safety Information for Apidra® (insulin glulisine injection)

Do not use Apidra if you have low blood sugar reaction or if you are allergic to insulin glulisine or any of the ingredients in Apidra.

Do not share needles, insulin pens or syringes with others even if the needle is changed. Do NOT reuse needles. You may give other people a serious infection, or get a serious infection from them.

Before starting Apidra, tell your doctor about all your medical conditions, including if you have liver or kidney problems, if you are pregnant or planning to become pregnant or if you are breastfeeding or planning to breastfeed.

Heart failure can occur if you are taking insulin together with pills called TZDs (thiazolidinediones), even if you never had heart failure or other heart problems. If you have heart failure, it may get worse while you take TZDs with Apidra. Your treatment with TZDs and Apidra may need to be changed or stopped by your doctor if you have new or worsening heart failure. Tell your doctor if you have new or worsening symptoms, including:

  • Shortness of breath
  • Sudden weight gain
  • Swelling of your ankles or feet

Tell your doctor about all medications you take, including OTC medicines, vitamins, supplements, and herbal supplements.

When used a mealtime insulin, Apidra should be taken within 15 minutes before a meal or within 20 minutes after starting a meal. Test your blood sugar levels as directed by your doctor when using Apidra. Do not change your dose or type of insulin without talking to your doctor. Any change of insulin should be made cautiously and only under medical supervision.

Check your insulin label to verify that you have the correct insulin before each injection. Use Apidra only if the solution is clear and colorless with no particles visible.

While using Apidra, do not drive or operate heavy machinery until you know how Apidra affects you. Do not drink alcohol or use medicines that contain alcohol.

Apidra may cause serious side effects that can lead to death, including:

  • Low blood sugar (hypoglycemia). Signs and symptoms of low blood sugar may include dizziness or light-headedness, sweating, confusion, headache, blurred vision, slurred speech, shakiness, fast heartbeat, anxiety, irritability or mood changes, hunger.
  • Serious allergic reactions. Get medical help right away if you have: a rash over your whole body, shortness of breath, trouble breathing, fast pulse, sweating or feeling faint
  • Low potassium in your blood (hypokalemia). Your doctor should monitor you for low blood potassium levels.
  • Heart failure. Your doctor should monitor you closely while you are taking TZDs with Apidra.

Get emergency medical help if you have:

  • Trouble breathing, shortness of breath, fast heartbeat, swelling of your face, tongue, or throat, sweating, extreme drowsiness, dizziness, confusion.

The most common side effects of APIDRA include: low blood sugar (hypoglycemia), weight gain, itching, rash, swelling, allergic reactions including injection site reactions, skin thickening or pits at the injection site (lipodystrophy)

Important Safety Information for Apidra® (insulin glulisine injection) SoloStar

Apidra SoloSTAR is a disposable prefilled insulin pen. Please talk to your healthcare provider about proper injection techniques and follow instructions in the Instruction Leaflet that accompanies the pen.

Important Safety Information for Apidra® (insulin glulisine injection) when used in a pump

Replace the infusion sets (reservoir, tubing, and catheter), and the Apidra in the reservoir at least every 48 hours and select a new infusion site. Do not mix or dilute Apidra when used in the pump. Failure of your insulin pump or infusion set or degradation of the insulin in the pump can cause hyperglycemia and ketoacidosis. Always carry an alternate form of insulin administration in the case of pump failure.

Click here for Full Prescribing Information for Apidra.
Click here for information on Sharps Medical Waste Disposal.
Click here to learn more about Sanofi's commitment to fighting counterfeit drugs.

If you are a patient experiencing problems with a Sanofi US product, please contact Sanofi US at 1-800-633-1610.

The health information contained herein is provided for general educational purposes only. Your healthcare professional is the single best source of information regarding your health. Please consult your healthcare professional if you have any questions about your health or treatment.

*

back to top ▲

*Eligibility Restrictions
This offer is not valid for prescriptions covered by or submitted for reimbursement under Medicare, Medicaid, VA, DOD, TRICARE, or similar federal or state programs including any state pharmaceutical assistance program. Important to note that if you have an Affordable Care (Health Care Exchange) plan, you may still be qualified to receive and use this savings card. Please note: the Federal Employees Health Benefits (FEHB) Program is not a federal or state government health care program for purposes of the savings program. Void where prohibited by law.

Savings may vary depending on patients’ out-of-pocket costs. Upon registration, patients receive all program details. Sanofi US reserves the right to change the maximum cap amount, rescind, revoke, or amend the program without notice.

Offer Terms for Apidra $0 Co-pay Savings Card
For the duration of the program, the Apidra Savings Card offers a $0 co-pay with a maximum savings of up to $100 per monthly prescription for patients covered by commercial/private insurance.

Offer Terms for Insulins Valyou Savings Program ($99)
Sanofi insulins included in this program are: APIDRA® (insulin glulisine injection) 100 Units/mL, ADMELOG® (insulin lispro injection), TOUJEO® (insulin glargine injection) 300 Units/mL and LANTUS® (insulin glargine injection) 100 Units/mL

This offer is not valid for prescriptions covered by commercial / private insurance. Only people without prescription medication insurance can apply for this offer. For the duration of the program, eligible patients will pay $99 for up to 10 vials (10mL) or packs of pens per fill. Offer is valid for one fill per month. In order for you to pay $99 per month, you must fill all your Sanofi Insulin prescriptions at the same time, together each month. When using the Insulins Valyou Savings Card, prices are guaranteed for 12 consecutive monthly fills. This offer is not valid for the Max SoloStar pen. The Insulins Valyou Savings Program applies to the cost of medication. There are other relevant costs associated with overall treatment.

© 2019 sanofi-aventis U.S. LLC. All rights reserved.

Legal Disclaimer | Privacy Policy | Contact SANOFI

This site is intended for use by U.S. residents only.

SAUS.GLU.18.12.7369b(1) Last Updated: May 2019

Important Safety Information for Apidra® (insulin glulisine injection)

Do not use Apidra if you have low blood sugar reaction or if you are allergic to insulin glulisine or any of the ingredients in Apidra.

Do not share needles, insulin pens or syringes with others even if the needle is not changed.
Do NOT reuse needles. You may give other people a serious infection, or get a serious infection from them.