Talking to your doctor

Be prepared for a conversation with your doctor. Use these discussion guides to help you get the most out of your next appointment—whether you’re just thinking about Apidra® or already using it.

Pick a guide to help lead a discussion with your doctor

Thinking about starting mealtime insulin

Learn about dosing options and talk with your healthcare professional about the Apidra dose that’s right for you.

3-6 month check-up

Make sure that you’re prepared for your next check-up with these helpful questions and conversation topics.

Annual check-up

This checklist contains important information for you to discuss with your healthcare professional during your annual check-up.

Monitoring blood sugar levels

Keeping a blood sugar log is a good way to help you and your healthcare professional make better decisions about your diabetes treatment plan.

Savings Offers

Learn how eligible patients with and without insurance can save on Apidra.

About Apidra

Learn how Apidra can help control blood sugar at mealtime and gives you dosing flexibility around mealtime.


Do you still have questions? Take a look at our frequently asked questions to get some more answers.

Indications and Usage for Apidra

Prescription Apidra is a fast (rapid) acting insulin used for adults and children with diabetes mellitus to control high blood sugar. It is not known if APIDRA is safe or effective in children less than 4 years of age with type 1 diabetes or in children with type 2 diabetes.

When used as a mealtime insulin, Apidra should be given within 15 minutes before or within 20 minutes after starting a meal.

Apidra may be infused subcutaneously by external insulin infusion pumps.

Important Safety Information

Do not use Apidra if you have low blood sugar reaction or if you are allergic to insulin glulisine or any of the ingredients in Apidra.

Do not share needles, insulin pens or syringes with others even if the needle is changed. Do NOT reuse needles. You may give other people a serious infection or get a serious infection from them.

Change (rotate) your injection sites within the area you chose with each dose to reduce your risk of getting lipodystrophy (pitted or thickened skin) and localized cutaneous amyloidosis (skin with lumps) at the injection sites. Do not use the same spot for each injection or inject where the skin is pitted, thickened, lumpy, tender, bruised, scaly, hard, scarred or damaged.

Before starting Apidra, tell your doctor about all your medical conditions, including if you have liver or kidney problems, if you are pregnant or planning to become pregnant or if you are breastfeeding or planning to breastfeed.

Heart failure can occur if you are taking insulin together with pills called TZDs (thiazolidinediones), even if you never had heart failure or other heart problems. If you have heart failure, it may get worse while you take TZDs with Apidra. Your treatment with TZDs and Apidra may need to be changed or stopped by your doctor if you have new or worsening heart failure. Tell your doctor if you have new or worsening symptoms, including:

  • Shortness of breath
  • Sudden weight gain
  • Swelling of your ankles or feet

Tell your doctor about all medications you take, including OTC medicines, vitamins, supplements, and herbal supplements.

When used a mealtime insulin, Apidra should be taken within 15 minutes before a meal or within 20 minutes after starting a meal. Test your blood sugar levels as directed by your doctor when using Apidra. Do not change your dose or type of insulin without talking to your doctor. Any change of insulin should be made cautiously and only under medical supervision.

Check your insulin label to verify that you have the correct insulin before each injection. Use Apidra only if the solution is clear and colorless with no particles visible.

While using Apidra, do not drive or operate heavy machinery until you know how Apidra affects you. Do not drink alcohol or use medicines that contain alcohol.

Apidra may cause serious side effects that can lead to death, including:

  • Low blood sugar (hypoglycemia). Signs and symptoms of low blood sugar may include dizziness or light-headedness, sweating, confusion, headache, blurred vision, slurred speech, shakiness, fast heartbeat, anxiety, irritability or mood changes, hunger.
  • Serious allergic reactions. Get medical help right away if you have: a rash over your whole body, shortness of breath, trouble breathing, fast pulse, sweating or feeling faint
  • Low potassium in your blood (hypokalemia). Your doctor should monitor you for low blood potassium levels.
  • Heart failure. Your doctor should monitor you closely while you are taking TZDs with Apidra.

Get emergency medical help if you have:

  • Trouble breathing, shortness of breath, fast heartbeat, swelling of your face, tongue, or throat, sweating, extreme drowsiness, dizziness, confusion.

The most common side effects of APIDRA include: low blood sugar (hypoglycemia), weight gain, itching, rash, swelling, allergic reactions including injection site reactions, skin thickening or pits at the injection site (lipodystrophy).

Important Safety Information for Apidra® (insulin glulisine injection) SoloStar®

Apidra SoloSTAR is a disposable single-patient-use prefilled insulin pen. Please talk to your healthcare provider about proper injection techniques and follow instructions in the Instruction Leaflet that accompanies the pen.

Important Safety Information for Apidra when used in a pump

Replace the infusion sets (reservoir, tubing, and catheter), and the Apidra in the reservoir at least every 48 hours and select a new infusion site. Do not mix or dilute Apidra when used in the pump. Failure of your insulin pump or infusion set or degradation of the insulin in the pump can cause hyperglycemia and ketoacidosis. Always carry an alternate form of insulin administration in the case of pump failure.

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If you are a patient experiencing problems with a Sanofi US product, please contact Sanofi US at 1-800-633-1610.

The health information contained herein is provided for general educational purposes only. Your healthcare professional is the single best source of information regarding your health. Please consult your healthcare professional if you have any questions about your health or treatment.

*Eligibility Restrictions & Offer Terms:

Insulins Valyou Savings Program:

Sanofi insulins included in this program are: ADMELOG® (insulin lispro injection) 100 Units/mL, TOUJEO® (insulin glargine injection) 300 Units/mL, LANTUS® (insulin glargine injection) 100 Units/mL and APIDRA® (insulin glulisine injection) 100 Units/mL.

This offer is not valid for prescriptions covered by or submitted for reimbursement under Medicare, Medicaid, VA, DOD, TRICARE, similar federal or state programs, including any state pharmaceutical programs, or commercial / private insurance. Only people without prescription medication insurance can apply for this offer. Void where prohibited by law. For the duration of the program, eligible patients will pay $99 for up to 10 vials or packs of SoloStar pens per fill or up to 5 packs of Max SoloStar pens per fill. Offer valid for one fill per month. To pay $99 per month, you must fill all your Sanofi Insulin prescriptions at the same time, together each month. Not valid for SOLIQUA 100/33 (insulin glargine and lixisenatide injection) 100 Units/mL and 33 mcg/mL. When using the Insulins Valyou Savings Card, prices are guaranteed for 12 consecutive monthly fills. The Insulins Valyou Savings Program applies to the cost of medication. There are other relevant costs associated with overall treatment.

Sanofi Copay Program:

This offer is not valid for prescriptions covered by or submitted for reimbursement under Medicare, Medicaid, VA, DOD, TRICARE, or similar federal or state programs including any state pharmaceutical assistance program. Important to note that if you have an Affordable Care (Health Care Exchange) plan, you may still be qualified to receive and use this savings card. Please note: the Federal Employees Health Benefits (FEHB) Program is not a federal or state government health care program for purposes of the savings program. Void where prohibited by law.

  • Apidra: $0 copay with maximum savings up to $100 per pack up to 1 pack per fill.

Savings may vary depending on patients’ out-of-pocket costs. Upon registration, patients receive all program details. Sanofi US reserves the right to change the maximum cap amount, rescind, revoke or amend these programs without notice.

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MAT-US-2016467-v2.0-03/2021 Last Updated: March 2021

Important Safety Information

Do not use Apidra if you have low blood sugar reaction or if you are allergic to insulin glulisine or any of the ingredients in Apidra.

Do not share needles, insulin pens or syringes with others even if the needle is changed. Do NOT reuse needles. You may give other people a serious infection, or get a serious infection from them.